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Brand name: epivir
Generic name: Lamivudine, Zeffix, Heptovir
epivir description:
One milliliter (1 mL) of Epivir-HBV Oral Solution contains 5 mg of lamivudine (5 mg/mL) in an aqueous solution and the inactive ingredients artificial strawberry and banana flavors, citric acid (anhydrous), methylparaben, propylene glycol, propylparaben, sodium citrate (dihydrate), and sucrose (200 mg). One case of an adult ingesting 6 g of EPIVIR was reported; there were no clinical signs or symptoms noted and hematologic tests remained normal. There was no significant difference in systemic exposure (AUC∞) in the fed and fasted states; therefore, Epivir-HBV Tablets and Oral Solution may be administered with or without food. If a decision is made to administer lamivudine to such patients, the higher dosage indicated for HIV therapy should be used as part of an appropriate combination regimen, and the prescribing information for EPIVIR, COMBIVIR, EPZICOM, or TRIZIVIR as well as for Epivir-HBV should be consulted. The safety and effectiveness of treatment with Epivir-HBV beyond 1 year have not been established. The study compared Epivir-HBV 100 mg once daily for 52 weeks, followed by either Epivir-HBV 100 mg or matching placebo once daily for 16 weeks (Arm 1), versus placebo once daily for 68 weeks (Arm 2).
epivir information at Drugs.com
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