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Brand name: gleevec
Generic name: Imatinib, Glivec
gleevec description:

The tumor cells carried an abnormality in a gene called KIT, so the patient was enrolled in a clinical trail of the drug imatinib (Gleevec), which targets the KIT gene. Gleevec had the most effect on tumors that were 10 cm or larger, less effect on tumors between 6 and 10 cm, and the least effect on tumors between 3 and 6 cm, the study reported. Gleevec is used to treat the following conditions: Acute Lymphoblastic Leukemia, Chronic Eosinophilic Leukemia, Chronic Myelogenous Leukemia, Dermatofibrosarcoma Protuberans, Gastrointestinal Stromal Tumor, Hypereosinophilic Syndrome, Myelodysplastic Diseases, Myeloproliferative Disorders, Systemic Mastocytosis. About one year into her treatment, the dose of Gleevec was increased to 600 milligrams per day, because she still had some cancer cells. While it's not possible to definitively prove that Gleevec caused premature menopause, Christopoulos said that based on the timing, the lack of other causes, and the drugs' mode of action, it's the most likely culprit. Gleevec is a member of the following drug classes: BCR-ABL tyrosine kinase inhibitors, tyrosine kinase inhibitors.

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