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Brand name: cozaar
Generic name: Losartan
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At the end of study or at the last visit before a primary endpoint, 77% of the group treated with Cozaar and 73% of the group treated with atenolol were still taking study medication. The overall incidence of adverse experiences reported with Cozaar was similar to placebo. However, the LIFE study provides no evidence that the benefits of Cozaar on reducing the risk of cardiovascular events in hypertensive patients with left ventricular hypertrophy apply to Black patients. In a clinical study conducted in type 2 diabetic patients with proteinuria, the incidence of hyperkalemia was higher in the group treated with Cozaar as compared to the placebo group; however, few patients discontinued therapy due to hyperkalemia (see ADVERSE REACTIONS). Compared with placebo, Cozaar significantly reduced proteinuria by an average of 34%, an effect that was evident within 3 months of starting therapy, and significantly reduced the rate of decline in glomerular filtration rate during the study by 13%, as measured by the reciprocal of the serum creatinine concentration. Treatment with Cozaar reduced the risk of stroke by 25% relative to atenolol (p=0.

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