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Organ Transplant, Rejection Prophylaxisazathioprine, cyclosporine, CellCept, Imuran, Prograf, tacrolimus, More. 5% survival in the Prograf plus MMF group and 86. The MMF dose was reduced to <2 g/day by month 12 in 62% of patients in the Prograf/MMF group (Table 7) and in 47% of patients in the cyclosporine/MMF group. In a 3-arm study conducted in the US, 331 patients received corticosteroids and Prograf plus sirolimus, Prograf plus mycophenolate mofetil (MMF) or cyclosporine modified plus MMF for 1 year. Patients randomized to Prograf/MMF were more likely to develop diarrhea and diabetes after the transplantation and experienced similar rates of infections compared to patients randomized to either cyclosporine/MMF regimen (see  ADVERSE REACTIONS).

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